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  • Maha S. Assadoon PharmD
  • Mary P. Kovacevic PharmD
  • Kevin M. Dube PharmD
  • Paul M. Szumita PharmD
  • Kenneth E. Lupi PharmD
  • Jeremy R. DeGrado PharmD
Journal of Intensive Care Medicine

Abstract

Introduction
Sedatives and analgesics are commonly utilized as continuous infusions in the ICU but have complications, including an increase in mechanical ventilation days, ICU length of stay, and delirium. Atypical antipsychotics (AAPs) affect several ...
Free accessResearch articleFirst published Jul 10, 2023
  • Kevin E. Anger PharmD, BCPS
  • Caryn Belisle RPh
  • Megan B. Colwell PharmD
  • Robert Dannemiller
  • Burhan Alawadhi PharmD
  • Alex Wilkocki PharmD
  • Paul M. Szumita PharmD, BCPS
Journal of Pharmacy Practice

Abstract

Calcium gluconate is preferred over calcium chloride for intravenous (IV) repletion of calcium deficiencies in the inpatient setting. In the setting of a national shortage of IV calcium gluconate, our institution implemented a compounded calcium chloride ...
Restricted accessResearch articleFirst published Dec 10, 2013
  • Kevin M. Dube PharmD, BCPS
  • Jeremy DeGrado PharmD, BCPS, BCCCP
  • Benjamin Hohlfelder PharmD, BCPS
  • Paul M. Szumita PharmD, FCCM, FASHP, BCPS, BCCCP
Journal of Pharmacy Practice

Abstract

Quetiapine, an atypical antipsychotic used in the intensive care unit (ICU) to manage delirium, has a possible adverse effect of corrected QT (QTc) interval prolongation. The objective of this analysis was to describe the impact of quetiapine on QTc ...
Restricted accessResearch articleFirst published Jun 6, 2017
  • Mary P. Kovacevic PharmD, BCPS
  • Paul M. Szumita PharmD, FCCM, FASHP, BCPS, BCCCP
  • Kevin M. Dube PharmD, BCPS, BCCCP
  • Jeremy R. DeGrado PharmD, BCPS, BCCCP
Journal of Pharmacy Practice

Abstract

Background:
The 2013 Society of Critical Care Medicine guidelines for the management of pain, agitation, and delirium in adult intensive care unit (ICU) patients recommend intravenous opioids as first-line therapy to treat nonneuropathic pain. There is a ...
Restricted accessResearch articleFirst published Jul 11, 2018
  • Lena K. Tran PharmD
  • Kevin E. Anger PharmD, BCPS
  • Heather Dell’Orfano PharmD, CACP, CPPS, BCPS
  • Megan A. Rocchio PharmD, BCPS
  • Paul M. Szumita PharmD, BCPS, BCCCP, FASHP, FCCM
Journal of Pharmacy Practice

Abstract

Objective:
To evaluate the cost, workflow, and safety of implementing a vial transfer device system.
Methods:
In this retrospective analysis, pharmacy systems and electronic health record reports identified high-volume and high-cost medications prepared by a ...
Free accessResearch articleFirst published Jul 8, 2020
  • Mohammed Aldhaeefi PharmD
  • Kevin M. Dube PharmD, BCCCP, BCPS
  • Mary P. Kovacevic PharmD, BCCCP, BCPS
  • Paul M. Szumita PharmD, FCCM, FASHP, BCCCP, BCPS
  • Kenneth E. Lupi PharmD, BCCCP, BCPS
  • Jeremy R. DeGrado PharmD, BCCCP, BCPS
Journal of Pharmacy Practice

Abstract

Background: Limited data exist to support the use of rocuronium continuous infusions in the intensive care unit (ICU). Objective: To evaluate the dosing and monitoring of adult patients who received rocuronium for hypoxemic respiratory failure during the ...
Restricted accessResearch articleFirst published Jul 19, 2021
  • Michael J. Corrado PharmD
  • Andrew Riselli PharmD
  • Kevin C. McLaughlin PharmD
  • Paul M. Szumita PharmD
  • Kevin E. Anger PharmD
Journal of Pharmacy Practice

Abstract

Background: Recent shortages of intravenous (IV) fluids have resulted in healthcare systems converting administration of many medications from IV piggyback (IVPB) to IV push (IVP). Administering medications via IVP presents numerous advantages; however, ...
Restricted accessResearch articleFirst published Aug 12, 2021
  • Nahal Beik PharmD, BCPS
  • Kevin E. Anger PharmD, BCPS
  • Allison A. Forni PharmD, BCPS
  • Komal Bawa PharmD, BCPS
  • Paul M. Szumita PharmD, BCPS
Annals of Pharmacotherapy

Abstract

Background: No previous studies exist examining implementation of an institution-wide guideline and order set for hyperglycemic emergencies (diabetic ketoacidosis [DKA] and hyperosmolar hyperglycemic state [HHS]). Objective: Evaluate the impact of an ...
Restricted accessResearch articleFirst published Nov 18, 2013
  • Rachel M. Blum PharmD, BCPS
  • Craig A. Stevens PharmD, BCPS
  • Danielle M. Carter PharmD, BCPS
  • Aaron P. Hussey PharmD, BCPS
  • Kathleen A. Marquis PharmD, BCPS
  • Heather Torbic PharmD, BCPS
  • Robert A. Southard PharmD, BCPS
  • Paul M. Szumita PharmD, BCPS
Annals of Pharmacotherapy

Abstract

Background: Brigham and Women’s Hospital implemented a dexmedetomidine stewardship program in October 2010 beginning with an institution-specific prescribing guideline. To ensure continued adherence to the prescribing guideline, a pharmacist-driven ...
Restricted accessResearch articleFirst published Nov 27, 2013
  • Kathleen A. Marquis PharmD, PhD
  • Jeremy R. DeGrado PharmD
  • Stephanie Labonville PharmD
  • David W. Kubiak PharmD
  • Paul M. Szumita PharmD
Annals of Pharmacotherapy

Abstract

Background: Consensus guidelines recommend vancomycin doses of 15 to 20 mg/kg every 8 to 12 hours in patients with normal renal function. Objective: To evaluate the effect of a pharmacist-directed vancomycin dosing and monitoring pilot program on the ...
Restricted accessResearch articleFirst published May 19, 2015